SE-ABA was delivered to the airline (also known as AB Aerotransport or just ABA) in March 1935 and became the flagship on ABA's Scandinavian Air Expressroute Malmö-Amsterdam. Powered by four 525 hp Pratt & Whitney Wasp engines, the aircraft could carry twenty-two passengers and four crew.
On June 9, 1936, three of the four engines cut out shortly after takeoff from Bulltofta Airport, Malmö, and the aircraft crashed. One of the passengers, Lawrence Kibbler, an American businessman, was killed, the aircraft damaged beyond repair.
The other three F.XXII's were produced for the Dutch airline KLM:
PH-AJP c/n 5357 "Papagaai" (Parrot)
PH-AJQ c/n 5358 "Kwikstaart" (Wagtail)
PH-AJR c/n 5360 "Roerdomp" (Bittern)